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Spatiotemporal Transcriptomic Profiling Reveals the Dynamic Immunological Landscape of Alveolar Echinococcosis

22 Feb 2025

Abstract excerpt

Abstract Alveolar echinococcosis (AE) is caused by the chronic infection of E. multilocularis , whose tumor‐like growth can lead to high fatality if improperly treated. The early diagnosis of infection and the treatment of advanced AE remain challenging. Herein, bulk RNA‐seq, scRNA‐seq, and spatial transcriptomics technologies are integrated, to reveal the host immune response mechanism against E. multilocularis...

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PMID: 39985260
DOI: 10.1002/advs.202405914

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