Article

Enteric viral infections promote systemic accelerated aging in Drosophila

2025-03-13

Abstract excerpt

Do viral infections accelerate aging, and does this acceleration scale with pathogenicity? Using transcriptomic aging clocks, we measured biological age in Drosophila infected with four enteric RNA viruses spanning a broad pathogenicity range (i.e. reduction of host lifespan). All pathogenic infections accelerated aging and the magnitude of acceleration tracked pathogenicity. This pattern held across oral and syst...

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Literature Corpus work: c472b494-4886-5ad5-ae55-dfb5b51465ed
DOI: 10.1101/2025.03.13.643076

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