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Article

Role of cilia in normal pancreas function and in diseased states

26 May 2014

Abstract excerpt

Primary cilia play an essential role in modulating signaling cascades that shape cellular responses to environmental cues to maintain proper tissue development. Mutations in primary cilium proteins have been linked to several rare developmental disorders, collectively known as ciliopathies. Together with other disorders associated with dysfunctional cilia/centrosomes, affected individuals have increased risk of...

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PMID: 24861006
DOI: 10.1002/bdrc.21064

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