Article

PathoGD: an integrative genomics approach for CRISPR-based target design of rapid pathogen diagnostics

2024-05-15

Abstract excerpt

<h4>ABSTRACT</h4> The design of highly specific primers and guide RNAs (gRNA) for CRISPR-based diagnostics is often a laborious process. Several tools exist for gRNA design, but most are tailored for genome editing applications. Here, we present PathoGD, an end-to-end bioinformatic pipeline comprising pangenome and k -mer modules for rapid and high-throughput design of primers and gRNAs for CRISPR-Cas12a-based p...

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Literature Corpus work: c3de04bc-d13a-5c0d-982a-f6ded28168e6
DOI: 10.1101/2024.05.14.593882

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