Article

Population-scale Characterization of the Oral Microbiome and Associations with Metabolic Health

2025-10-30

Abstract excerpt

The oral microbiome may capture system-specific information about host metabolic health, yet large-scale, multi-system evidence remains scarce. We analyzed 9,431 participants in the Human Phenotype Project (HPP), integrating buccal-swab oral whole-metagenome profiles with 44 metabolic measures spanning liver ultrasound, continuous glucose monitoring (CGM), and dual-energy X-ray absorptiometry (DXA). Using a microb...

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Literature Corpus work: c3aaa0a3-f617-571f-b701-cc806ac83069
DOI: 10.1101/2025.10.28.685004

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