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Article

Population-scale characterization of the oral microbiome and associations with metabolic health.

Nature communications - 9 May 2026

Xue Haochen, Godneva Anastasia, Tang Feilong, Li Huifa, Li Yulong, Hu Ming, Li Ruobing, Su Jionglong, Segal Eran, Razzak Imran

Abstract excerpt

The oral microbiome may capture system-specific information about host metabolic health, yet large-scale, multi-system evidence remains scarce. We analyzed 9,431 participants in the Human Phenotype Project (HPP), integrating buccal-swab oral whole metagenome profiles with 44 metabolic measures spanning liver ultrasound, continuous glucose monitoring (CGM), and dual energy X ray absorptiometry (DXA). Here we show...

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Identifiers

PMID: 42106335
DOI: 10.1038/s41467-026-72748-3
PMCID: PMC13376508

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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