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Article

Role of ferroptosis in hepatocellular carcinoma.

Journal of cancer research and clinical oncology - 1 Dec 2018

Nie Jianhua, Lin Binlin, Zhou Meng, Wu Li, Zheng Tongsen

Abstract excerpt

PURPOSE: Hepatocellular carcinoma (HCC) is a complicated disease with low survival rate due to frequent recurrence and the lack of efficient therapies. For advanced HCC, sorafenib, as the only approved first-line drug for HCC, improves the survival to some extent, but depressingly with severe adverse effects and emerging resistance conditions, which cause a poor prognosis. Ferroptosis is a new recognized way of...

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Share to Carcinogenesis
Share to Carcinoma, Hepatocellular
Share to Cell Death

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to Gene Expression Regulation, Neoplastic

Share to Lipid Metabolism

Share to Liver Neoplasms

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Source

Identifiers

PMID: 30167889
DOI: 10.1007/s00432-018-2740-3

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