Article

Synthesis of New Promising BNCT Agents Based on Conjugates of <i>closo</i>-Dodecaborate Anion and Aliphatic Diamino Acids

2024-12-02

Abstract excerpt

In this work, a series of boronated amidines based on the closo-dodecaborate anion and amino acids containing an amino group in the side chain of the general formula [B12H11NHC(NH(CH2)nCH(NH3)COOH)CH3], where n = 2, 3, 4, were synthesized. These derivatives contain conserved α-amino and α-carboxyl groups recognized by the binding centers of the large neutral amino acid transporter (LAT) system, which s...

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Literature Corpus work: c3987d30-871e-52ef-955f-19beb5fd2f8d
DOI: 10.20944/preprints202412.0021.v1

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