Back to search

Article

Paranoid schizophrenia and methamphetamine-induced paranoia are both characterized by a similar LINE-1 partial methylation profile, which is more pronounced in paranoid schizophrenia

2018-08-29

Abstract excerpt

<h4>Background</h4> There is evidence that schizophrenia is a neuro-immune disorder. Genes linked to intragenic LINE-1 methylation show a strong association with immune-associated disorders including psychosis. The aim of this study was to examine LINE-1 methylation patterns in paranoid schizophrenia and methamphetamine-induced paranoia, a model for schizophrenia. <h4>Methods</h4> This study recruited 31 patient...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
c38f3214-8e4f-5a54-b11f-ecccbd289834
DOI
10.1101/403535
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Paranoid schizophrenia and methamphetamine-induced paranoia are both characterized by a similar LINE-1 partial methylation profile, which is more pronounced in paranoid schizophreniaDOI 10.1101/403535
A subtype of schizophrenia patients with altered methylation level of genes related to immune cell activitySemantic proximity
Genome-wide DNA methylation analysis of peripheral blood cells derived from patients with first-episode schizophrenia in the Chinese Han populationSemantic proximity
Methylomic alteration in peripheral blood lymphocytes of prodromal stage and first-episode Chinese Han schizophrenia patientsSemantic proximity
Large-scale analysis of DNA methylation identifies cellular alterations in blood from psychosis patients and molecular biomarkers of treatment-resistant schizophreniaSemantic proximity
Methylation patterns in whole blood correlate with symptoms in schizophrenia patients.Semantic proximity
DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophreniaSemantic proximity
Elevated brain-derived cell-free DNA among patients with first psychotic episode – a proof-of-concept studySemantic proximity
Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia, part III: Molecular mechanismsSemantic proximity
Derivation of poly-methylomic profile scores for schizophrenia.Semantic proximity
Monocytic Subsets and Their Signature Genes Differentially Impact Cortex and Cognition in First-Episode SchizophreniaSemantic proximity
The novel pathway phenotype “major neurocognitive psychosis” is validated as a distinct class through the analysis of immune-linked neurotoxicity biomarkers and neurocognitive deficitsSemantic proximity
Association of a Reproducible Epigenetic Risk Profile for Schizophrenia With Brain Methylation and FunctionSemantic proximity
Select a neighboring publication to make it the new centre.