Article
Methylation patterns in whole blood correlate with symptoms in schizophrenia patients.
Schizophrenia bulletin - 1 Jul 2014
Liu Jingyu, Chen Jiayu, Ehrlich Stefan, Walton Esther, White Tonya, Perrone-Bizzozero Nora, Bustillo Juan, Turner Jessica A, Calhoun Vince D
Abstract excerpt
DNA methylation, one of the main epigenetic mechanisms to regulate gene expression, appears to be involved in the development of schizophrenia (SZ). In this study, we investigated 7562 DNA methylation markers in blood from 98 SZ patients and 108 healthy controls. A linear regression model including age, gender, race, alcohol, nicotine and cannabis use status, and diagnosis was implemented to identify...
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