Article

A loss-of-function variant in ZCWPW1 causes human male infertility with sperm head defect and high DNA fragmentation

2023-09-28

Abstract excerpt

<h4>Background: </h4> In about one-third of cases, the genetic causes of asthenozoospermia are unknown. The more causative genes related to human male infertility should be further explored. The essential role of ZCWPW1 in mouse male fertility has been established and the role of ZCWPW1 in human reproduction need further investigation to verify. Methods Whole-exome sequencing was conducted to identify causative g...

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Literature Corpus work: c31a3df3-9cfc-5101-b6c8-023a9e40eec8
DOI: 10.21203/rs.3.rs-3366901/v1

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