Article

Polygenic and environmental determinants of tics in the Avon Longitudinal Study of Parents and Children cohort

2021-05-12

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Tourette syndrome (TS) is caused by multiple genetic and environmental factors. Yet, little is known about the interplay of these factors in the occurrence of tics in the general population. <h4>METHODS</h4> Using logistic regression, we investigated whether polygenic risk score (PRS) of TS and pregnancy-related environmental factors together enhance the explained variance of...

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Literature Corpus work: c309e715-ed63-5505-808a-6415433e276f
DOI: 10.1101/2021.05.10.21256958

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