Article

Molecular subtyping and prognostic assessment based on tumor mutation burden in patients with lung adenocarcinomas

2019-02-25

Abstract excerpt

Tumor mutation burden (TMB) is a potential biomarker for response to immunotherapy. The subset of patients with TMB has not been well characterized in lung adenocarcinomas. Here we performed molecular subtyping based on TMB and compared the features of different subtypes including clinical features, somatic driver genes and mutational signatures. We found that patients with lower tumor mutation burden had a longer...

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Literature Corpus work: c2acad81-8f54-5818-92a0-e9cdbb5de01f
DOI: 10.1101/553461

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