Article
Prognostic Impact of Tumor Mutation Burden in Patients With Completely Resected Non-Small Cell Lung Cancer: Brief Report.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Aug 2018
Owada-Ozaki Yuki, Muto Satoshi, Takagi Hironori, Inoue Takuya, Watanabe Yuzuru, Fukuhara Mitsuro, Yamaura Takumi, Okabe Naoyuki, Matsumura Yuki, Hasegawa Takeo, Ohsugi Jun, Hoshino Mika, Shio Yutaka, Nanamiya Hideaki, Imai Jun-Ichi, Isogai Takao, Watanabe Shinya, Suzuki Hiroyuki
Abstract excerpt
INTRODUCTION: Tumor mutation burden (TMB) is thought to be associated with the amount of neoantigen in the tumor and to have an important role in predicting the effect of immune checkpoint inhibitors. However, the relevance of TMB to prognosis is not yet fully understood. In this study, we investigated the clinical significance of TMB in patients with NSCLC and examined the relationship between TMB and prognosis....
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