Article

MYBL2 maintains stemness and promotes theta-mediated end joining in triple negative breast cancer

2025-04-18

Abstract excerpt

Triple negative breast cancer (TNBC) has a poor prognosis due to limited treatment options and high metastasis risk. Breast cancer (BC) stem/progenitor cells, also known as tumour initiating cells, are a small, difficult to target population within the tumour responsible for metastasis and therapy resistance. MYBL2 overexpression is commonly linked to poor prognosis and metastasis but its role in BC stem/progenito...

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Literature Corpus work: c2ab8e6b-761d-5e71-aaee-b924f9c43b5f
DOI: 10.1101/2025.04.15.648875

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