Back to search

Article

Quantification of cyclin D1 and D2 proteins in multiple myeloma identifies different expression patterns from those revealed by gene expression profiling

2023-03-02

Abstract excerpt

<title>Abstract</title> <p>Upregulation of a cyclin D gene determined by expression microarrays is an almost universal event in MM, but this finding has not been properly confirmed at the protein level. For this reason, we carried out a quantitative analysis of cyclin D proteins using a capillary electrophoresis nanoimmunoassay in newly diagnosed MM patients. Exclusive expression of cyclin D1 and D2 proteins was...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
c24d43ab-724b-596c-b257-d8ad72545d43
DOI
10.21203/rs.3.rs-2616507/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Quantification of cyclin D1 and D2 proteins in multiple myeloma identifies different expression patterns from those revealed by gene expression profilingDOI 10.21203/rs.3.rs-2616507/v1
Amplification of cyclin D1 gene in multiple myeloma: clinical and prognostic relevanceSemantic proximity
Molecular Classification of Multiple Myeloma: A Distinct Transcriptional Profile Characterizes Patients Expressing <i>CCND1</i> and Negative for 14q32 TranslocationsSemantic proximity
Different mechanisms of cyclin D1 overexpression in multiple myeloma revealed by fluorescence in situ hybridization and quantitative analysis of mRNA levelsSemantic proximity
Cyclin D1 overexpression is a favorable prognostic variable for newly diagnosed multiple myeloma patients treated with high-dose chemotherapy and single or double autologous transplantationSemantic proximity
Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining.Semantic proximity
Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma.Semantic proximity
Molecular pathogenesis and a consequent classification of multiple myeloma.Semantic proximity
Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cellsSemantic proximity
Select a neighboring publication to make it the new centre.