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Closed-loop neurostimulation for epilepsy leads to improved outcomes when stimulation episodes are delivered during periods with less epileptiform activity

2022-11-29

Abstract excerpt

<h4>ABSTRACT</h4> In patients with drug-resistant epilepsy, electrical stimulation of the brain in response to epileptiform activity can make seizures less frequent and debilitating. When effective, this therapy, known as closed-loop responsive neurostimulation (RNS), produces long-lasting changes in brain dynamics that correlate with clinical outcomes. Since periods with frequent epileptiform activity are less co...

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Literature Corpus work
e4a887c6-99c7-57ac-a81b-ae917f2483fc
DOI
10.1101/2022.11.28.22282784
Open publication

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Closed-loop neurostimulation for epilepsy leads to improved outcomes when stimulation episodes are delivered during periods with less epileptiform activityDOI 10.1101/2022.11.28.22282784
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