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Deciphering the Immune Landscape of Head and Neck Squamous Cell Carcinoma: A Single-Cell Transcriptomic Analysis of Regulatory T Cell Responses to PD-1 Blockade Therapy

2023-05-02

Abstract excerpt

Immunotherapy is changing the Head and Neck Squamous Cell Carcinoma (HNSCC) landscape and improving outcomes for patients with recurrent or metastatic HNSCC. A deeper understanding of the tumor microenvironment (TME) is required in light of the limitations of patients' responses to immunotherapy. Here, we aimed to examine how Nivolumab affects infiltrating T regs in the HNSCC TME. We used single-cell RNA sequencin...

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Literature Corpus work
3f167322-81c8-5587-b8dc-5cc13ab1a431
DOI
10.21203/rs.3.rs-2812261/v1
Open publication

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Deciphering the Immune Landscape of Head and Neck Squamous Cell Carcinoma: A Single-Cell Transcriptomic Analysis of Regulatory T Cell Responses to PD-1 Blockade TherapyDOI 10.21203/rs.3.rs-2812261/v1
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