Article

WDR81 represses IKK mediated expression of pro-survival genes to regulate apoptosis

2025-03-27

Abstract excerpt

Apoptosis is a common host response to virus infection. The extent and timing of apoptosis following infection is controlled by the balance between the strength of signals that activate death signaling and those that promote the survival of cells. In many cell types, infection with Mammalian orthoreovirus (reovirus) results in induction of cell death by apoptosis late in infection. In this study, we uncovered that...

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Identifiers and source

Literature Corpus work: c186aa08-859e-55fa-90f4-18887f5559fd
DOI: 10.1101/2025.03.27.645662

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