Article

Pharmacology and pharmacodynamics of selected antimalarials against P. falciparum gametocytes

2017-01-01

Abstract excerpt

Malaria is a vector-borne disease that is still responsible for high human morbidity and mortality. Of the five Plasmodium species that can cause malaria in humans, Plasmodium falciparum is regarded the most virulent species. The most fundamental component of sustained control and eradication efforts is the development of effective drugs for malaria treatment and prophylaxis. Plasmodium falciparum’s sexual stages...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8fdb6ff6-a991-5259-8e6f-58550da05311
DOI: 10.17638/03005700

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Pharmacology and pharmacodynamics of selected antimalarials against P. falciparum gametocytesDOI 10.17638/03005700Read

Effects of Antimalarial Molecules on the Gametocyte Stage of <i>Plasmodium falciparum</i>: The DebateSemantic proximity Read

Identification of Antimalarial Inhibitors Using Late-Stage Gametocytes in a Phenotypic Live/Dead Assay.Semantic proximity Read

Luciferase-Based, High-Throughput Assay for Screening and Profiling Transmission-Blocking Compounds against Plasmodium falciparum GametocytesSemantic proximity Read

Malaria gametocytogenesisSemantic proximity Read

Targeting Gametocytes of the Malaria Parasite Plasmodium falciparum in a Functional Genomics Era: Next StepsSemantic proximity Read

Phenotypic Screening of Small Molecules with Antimalarial Activity for Three Different Parasitic Life Stages.Semantic proximity Read

Promising antimalarial hits from phenotypic screens: a review of recently-described multi-stage actives and their modes of actionSemantic proximity Read

Adapt or Die: Targeting Unique Transmission-Stage Biology for Malaria EliminationSemantic proximity Read

Cell based assays for anti-Plasmodium activity evaluation.Semantic proximity Read

Identification of MMV Malaria Box Inhibitors of Plasmodium falciparum Early-Stage Gametocytes Using a Luciferase-Based High-Throughput AssaySemantic proximity Read

A Research Agenda for Malaria Eradication: Basic Science and Enabling TechnologiesSemantic proximity Read

Gametogenesis in Plasmodium: Delving Deeper to Connect the DotsSemantic proximity Read