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The Outcome of Bisphosphonate-Related Osteonecrosis of the Jaw Patients’ Gingiva-Derived Mesenchymal Stem Cells on Wound Healing in a Mice Excisional Skin Model.

2021-01-07

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Retarded gingival healing is the hallmark of bisphosphonate-related osteonecrosis of the jaw (BRONJ) and poses a great challenge to maxillofacial surgeons. Although previous studies have showed that bisphosphonates (BPs) are highly toxic to healthy gingival mesenchymal stem cells (GMSCs) in vitro, there is overall lack of direct evidence demonstrating the regene...

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Literature Corpus work
c13faab2-82d4-5945-a24e-508522855b49
DOI
10.21203/rs.3.rs-139953/v1
Open publication

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