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Pan-cancer landscape of CENPO and its underlying mechanism in LUAD

15 Apr 2023

Abstract excerpt

BACKGROUND: Centromere protein O (CENPO) is a newly discovered constitutive centromeric protein, associated with cell death. However, little is known about how CENPO expression is associated with human cancers or immune infiltration. Here, we assessed the function of CENPO in pan-cancer and further verified the results in lung adenocarcinoma (LUAD) through in vitro and in vivo experiments. METHODS: Sangerbox and...

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PMID: 37061713
DOI: 10.1186/s12931-023-02408-3

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