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A pyrimidine metabolism-related gene signature for prognosis prediction and immune microenvironment description of breast cancer

23 Jun 2025

Abstract excerpt

BACKGROUND: Metabolic reprogramming is a hallmark in cancer. Pyrimidine metabolism (PM), a part of nucleotide metabolism, has been shown to be associated with the progression of various cancers, and the prognostic predictive ability of pyrimidine metabolism-related genes (PMG) in breast cancer has not been elucidated. This paper was designed to identify pyrimidine metabolism-related prognostic marker of breast...

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PMID: 40551112
DOI: 10.1186/s12967-025-06700-2

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