Article

Unraveling the Global Proteome and Phosphoproteome of Prostate Cancer Patient-Derived Xenografts

2023-08-05

Abstract excerpt

Resistance to androgen deprivation therapies leads to metastatic castration-resistant prostate cancer (mCRPC) of adenocarcinoma (AdCa) origin that can transform to emergent aggressive variant prostate cancer (AVPC) which has neuroendocrine (NE)-like features. To this end, we used LuCaP patient-derived xenograft (PDX) tumors, clinically relevant models that reflects and retains key features of the tumor from advanc...

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Literature Corpus work: c0de6e7c-55d8-5537-8ce8-96ef63db1033
DOI: 10.1101/2023.08.02.551697

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