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Modeling neurodegenerative diseases in <i>Drosophila</i> is conditioned by stress resistance and gut microbiome composition of the reference line

2025-09-08

Abstract excerpt

Drosophila is widely used to study the pathological mechanisms of human diseases in vivo , including metabolic and neurological disorders. In these models, disease-induced alterations in locomotion and stress resistance are generally monitored in comparison to healthy control flies, such the white-eyed strain w 1118 , used as a reference for normal physiology and behavior. Here we compared two independent w 111...

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Literature Corpus work
c0d2593f-4744-587c-8756-0cd9750c2d53
DOI
10.1101/2025.09.03.673979
Open publication

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Modeling neurodegenerative diseases in <i>Drosophila</i> is conditioned by stress resistance and gut microbiome composition of the reference lineDOI 10.1101/2025.09.03.673979
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