Article

Genetic risk factors have a substantial impact on healthy life years

2022-01-28

Abstract excerpt

The impact of genetic variation on overall disease burden has not been comprehensively evaluated. Here we introduce an approach to estimate the effect of different types of genetic risk factors on disease burden quantified through disability-adjusted life years (DALYs, “lost healthy life years”). We use genetic information from 735,748 individuals with registry-based follow-up of up to 48 years. At the individual...

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Literature Corpus work: c0ad1bf6-5cf8-5e9a-be3d-289d3dc10446
DOI: 10.1101/2022.01.25.22269831

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