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Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanisms

2025-02-11

Abstract excerpt

mRNA vaccines against SARS-CoV-2 were rapidly developed and were effective during the pandemic. However, some limitations remain to be resolved, such as the short-lived induced immune response and certain adverse effects. Therefore, there is an urgent need to develop new vaccines that address these issues. While live-attenuated vaccines are a highly effective modality, they pose a risk of adverse effects, includin...

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Literature Corpus work
c098cb34-ad0e-588f-93ce-34aa1d4ee91f
DOI
10.7554/elife.97532.3
Open publication

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Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanismsDOI 10.7554/elife.97532.3
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