Article

Pathogenicity, immunogenicity, and protective ability of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein

2020-09-24

Abstract excerpt

<title>Abstract</title> <p>SARS-CoV-2 is zoonotic origin and contains a PRRA polybasic cleavage motif which is considered critical for efficient infection and transmission in humans. We previously reported on a panel of attenuated SARS-CoV-2 variants with deletion at the S1/S2 junction of spike protein. Here we characterize pathogenicity, immunogenicity, and protective ability of a further cell-adapted SARS-CoV-2...

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Literature Corpus work: 96001714-320f-54b4-af89-7043744c34a9
DOI: 10.21203/rs.3.rs-78635/v1

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