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Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanisms

2024-03-04

Abstract excerpt

mRNA vaccines against SARS-CoV-2 were rapidly developed and effective during the pandemic. However, some limitations remain to be resolved, such as the short-lived induced immune response and certain adverse effects. Therefore, there is an urgent need to develop new vaccines that address these issues. While live-attenuated vaccines are a highly effective modality, they pose a risk of adverse effects, including vir...

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Literature Corpus work
a466baf5-952c-5190-b08c-dfadb47b66ab
DOI
10.1101/2024.03.03.582873
Open publication

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Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanismsDOI 10.1101/2024.03.03.582873
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