Article

A Novel Gene Mutation of PIK3R1EY451delinsD in Breast Cancer with the Resistance to HER2-targeted Therapy

2020-10-16

Abstract excerpt

Previously, little is known about the relationship between the PIK3R1 mutation status and the resistance to HER2-targeted therapies. Herein, we report a HER2-positive breast cancer patient with PIK3R1EY451delinsD showed resistance to HER2-targeted therapy, and adding everolimus to the treatment of trastuzumab and carboplatin achieved better effect.

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Literature Corpus work: c0680a98-baf7-5780-98ed-3ac579cfee65
DOI: 10.22541/au.160288153.32381176/v1

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