Article

The biophysical mechanism of mitochondrial pearling

2024-12-22

Abstract excerpt

Mitochondrial networks exhibit remarkable dynamics that are driven in part by fission and fusion events. However, there are other reorganizations of the network that do not involve fission and fusion. One such exception is the elusive, “beads-on-a-string” morphological transition of mitochondria. During such transitions, the cylindrical tubes of the mitochondrial membrane transiently undergo shape changes to a str...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c044fc24-041c-5bdd-9861-f7397b303d86
DOI: 10.1101/2024.12.21.629509

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The biophysical mechanism of mitochondrial pearlingDOI 10.1101/2024.12.21.629509Read

Force-induced tail-autotomy mitochondrial fission and biogenesis of matrix-excluded mitochondrial-derived vesicles for quality controlSemantic proximity Read

A shape shifting organelle: unusual mitochondrial phenotype determined with three-dimensional electron microscopy reconstructionSemantic proximity Read

The Curse of the Red Pearl: A Fibroblast-Specific Pearl-Necklace Mitochondrial Phenotype Caused by Phototoxicity.Semantic proximity Read

Move it to lose it: Mitocytosis expels damaged mitochondriaSemantic proximity Read

Pathogenic DRP1 variants reveal a role for biomolecular condensation in mitochondrial fissionSemantic proximity Read

Disentangling the biological information encoded in disordered mitochondrial morphology through its rapid elicitation by iCMMSemantic proximity Read

Nucleus-Tethered Mitochondria are essential for Ca²⁺ homeostasisSemantic proximity Read

Emergence of tunneling nanotube-like intervesicular connectionsSemantic proximity Read

Mitochondrial morphological features are associated with fission and fusion events.Semantic proximity Read

Principles of the mitochondrial fusion and fission cycle in neurons.Semantic proximity Read

When mitochondria fall apart: Unbalanced mitochondrial segregation triggers loss of mtDNA in the absence of mitochondrial fusionSemantic proximity Read

Class-I myosin responds to changes in membrane tension during clathrin-mediated endocytosis in human induced pluripotent stem cellsSemantic proximity Read