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White Matter Hyperintensity Burden Modifies the Association Between Atrial Fibrillation and Cerebral Microbleeds

2026-06-08

Abstract excerpt

<h4>Background</h4> In atrial fibrillation (AF), cerebral microbleed (CMB) burden guides anticoagulation decisions, yet AF is itself inconsistently associated with CMBs, a paradox unexplained by frameworks that treat CMBs as a unitary marker of small vessel disease. We hypothesized that the white matter hyperintensity (WMH) context in which CMBs arise modifies their vascular meaning, and that this context-depende...

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Literature Corpus work
c0100333-481c-5972-bb67-87f9b81294af
DOI
10.64898/2026.06.03.26354875
Open publication

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