Article

Location patterns and longitudinal progression of white matter hyperintensities

2026-02-23

Abstract excerpt

<h4>Background and Objectives</h4> White matter hyperintensities (WMH) of presumed vascular origin are a neuroimaging hallmark of cerebral small vessel disease (CSVD). Their spatial heterogeneity may reflect different clinical phenotypes. Most prior studies relied on principal component analysis to characterise such heterogeneity, which has limited ability to stratify individuals into discrete and interpretable W...

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Literature Corpus work: 20303109-b711-56cf-b1a6-6a4a425e8331
DOI: 10.64898/2026.02.20.26346709

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