Article

Prioritization of driver genes in cancer-associated copy number alterations identifies B4GALT5 as a glycooncogene

2022-04-01

Abstract excerpt

Cancer is a disease resulting from aberrant communication between cells of a multicellular organism. The glycan coat that surrounds the cells is an important player in cellular communication. While altered cell surface glycans are known biomarkers for cancer, glycan biosynthesis itself has not been considered a potential oncogenic pathway. So, to understand the oncogenic potential of the glycan biosynthetic pathwa...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bffbb2eb-e8b3-50e7-bf7d-3dce020764f1
DOI: 10.1101/2022.03.30.486261

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Prioritization of driver genes in cancer-associated copy number alterations identifies B4GALT5 as a glycooncogeneDOI 10.1101/2022.03.30.486261Read

Key Cancer Glycosylation-related Genes Analysis: Regulatory, Therapeutic, and Prognostic InsightsSemantic proximity Read

Differential expression of glycosyltransferases identified through comprehensive pan-cancer analysisSemantic proximity Read

The transcriptional landscape of glycosylation-related genes in cancerSemantic proximity Read

Pan-cancer metabolic landscapes: A multi-omics viewSemantic proximity Read

Spatial Glyco-Codes Define Human Liver Pathology and ProgressionSemantic proximity Read

A Wide-angle Glance Of Phosphoglucomutase Gene Family In Pan-CancerSemantic proximity Read

Integrated multi-omics analysis and machine learning based on O_linked_glycosylation genes refine molecular subtypes and prognosis for hepatocellular carcinomaSemantic proximity Read

Decoding the Glycan Signature: Unraveling <i>N</i> -Glycosylation Alterations in Glycogen Storage Disease Ia and IbSemantic proximity Read

Glycosyltransferase Gene Expression Profiles Classify Cancer Types and Propose Prognostic Subtypes.Semantic proximity Read

Identification of GBN5 as a molecular biomarker of pan-cancer species by integrated multi-omics analysisSemantic proximity Read

Integrating Transcriptomics, Glycomics And Glycoproteomics To Characterize Hepatitis B Virus-associated Hepatocellular CarcinomaSemantic proximity Read

Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer.Semantic proximity Read