Back to search

Article

Integrated multi-omics analysis and machine learning based on O_linked_glycosylation genes refine molecular subtypes and prognosis for hepatocellular carcinoma

2023-12-06

Abstract excerpt

<title>Abstract</title> <p>O-glycosylation exerts significant influence on cellular physiological processes and disease regulation by modulating the structure, function, and stability of proteins. However, there is still a lack of research focusing on O-glycosylation in relation to the prognosis of HCC patients. Here we explored expression and function of O-glycosylation gene in HCC from both bulk and single-cell...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
636805f8-bbf3-5f62-b0dd-e9dddcbdd397
DOI
10.21203/rs.3.rs-3700057/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Integrated multi-omics analysis and machine learning based on O_linked_glycosylation genes refine molecular subtypes and prognosis for hepatocellular carcinomaDOI 10.21203/rs.3.rs-3700057/v1
Glycosylation-Related Genes predict prognosis in Hepatocellular carcinomaSemantic proximity
Bioinformatic analysis and in vitro experiments reveal that N-linked glycosylation related genes STT3A, DDOST and TMEM165 participate in the promotion of hepatocellular carcinoma and Its role in immunotherapySemantic proximity
Comprehensive Bioinformatics Analysis of Glycosylation-Related Genes and Potential Therapeutic Targets in Colorectal CancerSemantic proximity
Integrating Transcriptomics, Glycomics And Glycoproteomics To Characterize Hepatitis B Virus-associated Hepatocellular CarcinomaSemantic proximity
A Novel Glycosylation-Related Transcriptome Panel with Immune and Clinical Value Predicts Prognosis and Drug Sensitivity in Clear Cell Renal Cell CarcinomasSemantic proximity
Key Cancer Glycosylation-related Genes Analysis: Regulatory, Therapeutic, and Prognostic InsightsSemantic proximity
A glycosylation-related signature can predict prognosis and immunotherapy response in patients with acute myeloid leukaemiaSemantic proximity
Glycosylation modification identifies novel molecular phenotypes and prognostic stratifications of glioma.Semantic proximity
Spatial Glyco-Codes Define Human Liver Pathology and ProgressionSemantic proximity
Prognostic modeling of glycosylation in TNBC and screening of related key genes through a comprehensive analysis of multi-omics studiesSemantic proximity
Molecular Subtypes of Esophageal Squamous Cell Carcinoma Driven by N- Glycosylation and Construction of a Machine Learning-Based Prognostic ModelSemantic proximity
Glycosylation‐Related Genes Predict the Prognosis and Immune Fraction of Ovarian Cancer Patients Based on Weighted Gene Coexpression Network Analysis (WGCNA) and Machine LearningSemantic proximity
Select a neighboring publication to make it the new centre.