Article
Glycosyltransferase Gene Expression Profiles Classify Cancer Types and Propose Prognostic Subtypes.
Scientific reports - 20 May 2016
Ashkani Jahanshah, Naidoo Kevin J
Abstract excerpt
Aberrant glycosylation in tumours stem from altered glycosyltransferase (GT) gene expression but can the expression profiles of these signature genes be used to classify cancer types and lead to cancer subtype discovery? The differential structural changes to cellular glycan structures are predominantly regulated by the expression patterns of GT genes and are a hallmark of neoplastic cell metamorphoses. We found...
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