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Human trophoblast stem cells can be used to model placental susceptibility to <i>Toxoplasma gondii</i> and highlight the critical importance of the trophoblast cell surface in pathogen resistance

2023-11-11

Abstract excerpt

<h4>ABSTRACT</h4> The placenta is a critical barrier against viral, bacterial, and eukaryotic pathogens. For most teratogenic pathogens, the precise molecular mechanisms of placental resistance are still being unraveled. Given the importance to understand these mechanisms and challenges in replicating trophoblast- pathogen interactions using in vitro models, we tested an existing stem-cell derived model of trop...

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Literature Corpus work: bfafdffb-ae0d-54d3-815e-220ce09fe82c
DOI: 10.1101/2023.11.10.566663

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