Article

How quickly can we predict trimethoprim resistance using alchemical free energy methods?

2020-01-14

Abstract excerpt

The emergence of antimicrobial resistance (AMR) threatens modern medicine and necessitates more personalised treatment of bacterial infections. Sequencing the whole genome of the pathogen(s) in a clinical sample offers one way to improve clinical microbiology diagnostic services, and has already been adopted for tuberculosis in some countries. A key weakness of a genetics clinical microbiology is it cannot return...

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Literature Corpus work: bf2395b4-b1e8-589f-abef-e458b72f8f24
DOI: 10.1101/2020.01.13.904664

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