Article

The human-specific miR-6762-5p is an activator of RhoA GTPase enhancing <i>Shigella flexneri</i> intercellular spreading

2022-11-28

Abstract excerpt

MicroRNAs have recently emerged as major players in host-bacterial pathogens interaction, either as part of the host defense mechanism to neutralize infection or as a bacterial arsenal aimed at subverting host cell functions. Here we identify the newly evolutionary emerged human microRNA miR-6762-5p as a new player in the host- Shigella interplay. A microarray analysis in infected epithelial cells allowed the det...

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Literature Corpus work: bf19ef4e-d156-58c4-84ed-b3480c12ec03
DOI: 10.1101/2022.11.28.518194

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