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Article

Shigella-mediated immunosuppression in the human gut: subversion extends from innate to adaptive immune responses

9 Apr 2019

Abstract excerpt

The enteropathogen, Shigella, is highly virulent and remarkably adjusted to the intestinal environment of its almost exclusive human host. Key for Shigella pathogenicity is the injection of virulence effectors into the host cell via its type three secretion system (T3SS), initiating disease onset and progression by the vast diversity of the secreted T3SS effectors and their respective cellular targets. The...

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PMID: 30964713
DOI: 10.1080/21645515.2019.1594132

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