Exploring the causal role of the human gut microbiome in endometrial cancer: a Mendelian randomization approach

Abstract excerpt

<h4>ABSTRACT</h4> Endometrial cancer presents a major public health issue, particularly in post-menopausal women. Whilst there are known risk factors for the disease, including oestrogen and obesity, these factors do not fully explain risk variability in cancer outcomes. The identification of novel risk factors may aid in better understanding of endometrial cancer development and, given the link with oestrogen met...

Topics

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• Colorectal Cancer Screening and Detection
• Endometriosis Research and Treatment
• Gastrointestinal Microbiome
• Genetic factors in colorectal cancer
• Genome-Wide Association Study
• Gut microbiota and health
• Mendelian Randomization Analysis
• Polymorphism, Single Nucleotide

Identifiers and source

Literature Corpus work

bf13b4b5-6ead-5abd-bd90-a486c11359f4

DOI

10.1101/2024.03.06.24303765