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Article

Gut microbiota and risk of five common cancers: A univariable and multivariable Mendelian randomization study.

Cancer medicine - 1 May 2023

Wei Zixin, Yang Biying, Tang Tiantian, Xiao Zijing, Ye Fengzhan, Li Xiaoyu, Wu Shangbin, Huang Jin-Gang, Jiang Shanping

Abstract excerpt

BACKGROUND: Previous studies have linked gut microbiota with cancer etiology, but the associations for specific gut microbiota are causal or owing to bias remain to be elucidated. METHODS: We performed a two-sample Mendelian randomization (MR) analysis to assess the causal effect of gut microbiota on cancer risk. Five common cancers, including breast, endometrial, lung, ovarian, and prostate cancer as well as...

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Identifiers

PMID: 36880394
DOI: 10.1002/cam4.5772
PMCID: PMC10225193

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