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Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 inflammasome Activity and Activating Nrf2 Signaling

2020-04-28

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Multiple sclerosis (MS), an autoimmune and degenerative disease, is characterized by demyelination and chronic neuroinflammation.Bixin is a carotenoid isolated from the seeds of <italic>Bixa orellana</italic> that exhibits various potent pharmacological activities, including antioxidant, anti-inflammation, and anti-tumor. However, the effects of bixin on MS remai...

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Literature Corpus work
bed114b4-1629-5bc1-a5e5-b90446d8798d
DOI
10.21203/rs.3.rs-24795/v1
Open publication

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