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Characterization and Purification of the Mammalian COP9 Complex, a Conserved Nuclear Regulator Initially Identified as a Repressor of Photomorphogenesis in Higher Plants

1998-08-01

Abstract excerpt

Abstract The COP9 complex has been identified as a repressor of photomorphogenesis in Arabidopsis. Here we demonstrate that the COP9 complex is also present in mammals. Specific antibodies were generated against human counterparts of the Arabidopsis COP9 and COP11, the two known subunits of plant COP9 complex. Using these antibodies, we showed that indeed mammalian COP9 and COP11, also known as GPS1, could be coim...

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Literature Corpus work
bec22f85-3773-51d5-9128-ca142a212b3a
DOI
10.1111/j.1751-1097.1998.tb02495.x
Open publication

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Characterization and Purification of the Mammalian COP9 Complex, a Conserved Nuclear Regulator Initially Identified as a Repressor of Photomorphogenesis in Higher PlantsDOI 10.1111/j.1751-1097.1998.tb02495.x
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