Article

UGP2, a novel target gene of TP53, inhibits endothelial cells apoptosis and atherosclerosis

2022-06-03

Abstract excerpt

<title>Abstract</title> <p> Dysfunction of the endothelial lining of lesion-prone areas of the arterial vasculature is an important contributor to the pathobiology of atherosclerotic cardiovascular disease. Recent studies have indicated that UDP-glucose pyrophosphorylase 2(UGP2) is implicated in cell proliferation and survival. Here we investigated the anti-apoptosis and anti-atherogenic effect of UGP2 in vitro...

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Literature Corpus work: bec1739a-22d7-508f-8e85-9ef131b9a560
DOI: 10.21203/rs.3.rs-1658149/v2

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