Article

Discovering novel long non-coding RNA predictors of anticancer drug sensitivity beyond protein-coding genes

2019-06-10

Abstract excerpt

Large-scale cancer cell line screens have identified thousands of protein-coding genes (PCGs) as biomarkers of anticancer drug response. However, systematic evaluation of long non-coding RNAs (lncRNAs) as pharmacogenomic biomarkers has so far proven challenging. Here, we study the contribution of lncRNAs as drug response predictors beyond spurious associations driven by correlations with proximal PCGs, tissue-line...

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Literature Corpus work: be7f1a30-b4ce-5449-9cc9-95ec8f77fd80
DOI: 10.1101/666156

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