Article

An empirical Bayes method for serotype case-carrier ratios, with an application to Group B streptococcus

2018-09-20

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Case-carrier ratios quantifying the relative pathogenicity of serotypes can inform vaccine formulations for antigenically-diverse pathogens. However, sparse serotype-specific counts in epidemiologic datasets may undermine such analyses, most notably for rare serotypes that pose emergence risks in vaccinated populations. This challenge is well-illustrated in Group B streptoco...

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Literature Corpus work: bddf6f78-2078-54d3-8b9a-d790c6d71e28
DOI: 10.1101/421412

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