Back to search

Article

Post-surgery level of circulating DNA in stage III colon cancer patients: impact on the reliability of minimal residual disease detection

2025-04-06

Abstract excerpt

<h4>Purpose</h4> Minimal residual disease (MRD) assessment guided by circulating DNA (cir-nDNA) testing is strongly prognostic in operable colon cancer patients. However, further clinical research to result in fully changing the clinical management of colon cancer about the use of adjuvant therapy. <h4>Experimental Design</h4> In order to improve the analytical signal sensitivity of MRD detection we investigated t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
bdcb8970-ad11-52eb-84e5-2784e73d4b68
DOI
10.1101/2025.04.04.25324955
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Post-surgery level of circulating DNA in stage III colon cancer patients: impact on the reliability of minimal residual disease detectionDOI 10.1101/2025.04.04.25324955
Minimal residual disease detection with circulating tumor DNA in colorectal cancer: current horizons and future perspectives in clinical applicationsSemantic proximity
Analysis of Plasma Cell-Free DNA by Ultradeep Sequencing in Patients With Stages I to III Colorectal CancerSemantic proximity
Finding Waldo: The Evolving Paradigm of Circulating Tumor DNA (ctDNA)-Guided Minimal Residual Disease (MRD) Assessment in Colorectal Cancer (CRC)Semantic proximity
Targeted next-generation sequencing of circulating-tumor DNA for tracking minimal residual disease in localized colon cancerSemantic proximity
Dynamic monitoring of circulating tumor DNA to predict prognosis and efficacy of adjuvant chemotherapy after resection of colorectal liver metastases.Semantic proximity
Beyond Binary MRD: Quantitative ctDNA Interpretation After Curative-Intent Surgery for Colorectal CancerSemantic proximity
Analysis of the clinical value of postoperative circulating tumor DNA (ctDNA) within the first month for resected colorectal cancer in a real-world.Semantic proximity
Colorectal Cancer Recurrence Prediction Using a Tissue-Free Epigenomic Minimal Residual Disease AssaySemantic proximity
Circulating cell-free nucleosomes as biomarkers for early detection of colorectal cancerSemantic proximity
Circulating and stool nucleic acid analysis for colorectal cancer diagnosis.Semantic proximity
Neutrophil extracellular traps have auto-catabolic activity and produce mononucleosome-associated circulating DNASemantic proximity
Relationship between post-surgery detection of methylated circulating tumor DNA with risk of residual disease and recurrence-free survival.Semantic proximity
Select a neighboring publication to make it the new centre.