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Beyond Binary MRD: Quantitative ctDNA Interpretation After Curative-Intent Surgery for Colorectal Cancer

2026-03-10

Abstract excerpt

<h4>Background</h4> Circulating tumor DNA (ctDNA) detection after curative-intent surgery is being used to identify minimal residual disease (MRD) in colorectal cancer (CRC). However, MRD classification is dependent on analytical sensitivity, and the impact of detection threshold on observed post-operative positivity remains incompletely characterized. We evaluated MRD positivity in stage I–III CRC using a CRISPR...

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Literature Corpus work
181251e9-8a45-53ef-a3f3-525eba102dcd
DOI
10.64898/2026.03.09.26347910
Open publication

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Beyond Binary MRD: Quantitative ctDNA Interpretation After Curative-Intent Surgery for Colorectal CancerDOI 10.64898/2026.03.09.26347910
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