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Article

Skeletal muscle characteristics are preserved in hTERT/cdk4 human myogenic cell lines

1 Dec 2016

Abstract excerpt

BACKGROUND: hTERT/cdk4 immortalized myogenic human cell lines represent an important tool for skeletal muscle research, being used as therapeutically pertinent models of various neuromuscular disorders and in numerous fundamental studies of muscle cell function. However, the cell cycle is linked to other cellular processes such as integrin regulation, the PI3K/Akt pathway, and microtubule stability, raising the...

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PMID: 27931240
DOI: 10.1186/s13395-016-0115-5

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